Microsoft Defender error - "this program cannot search for definition updates"

Have you ever come across the error - "this program cannot search for definition updates" on your Microsoft Windows Defender while trying to update the software?

If yes is the answer then either
your version of defender is not compatible with the update engine used by Microsoft or
the update client for the defender insalled on your PC is corrupted by a spyware, virus or trojan.

Now, here comes the solution...

Open the URL - Microsoft Malware Protection Center

Under the section - Latest Definition Updates --> Windows Defender
Antispyware click on the 32 bit or 64 bit matching the version of Windows installed on your PC.

Save the setup file and run it. Once the update is complete, open windows defender and try to run the update manually. You won't get the error anymore. :-)